Credentials MBBS (Singapore) 1973, MRCP (Int Med) (UK) 1979, FAMS (Gastroenterology) 1983, FRCP (Int Med) (Edin) 1990, FRCP (Int Med) (Lond) 1992
Language English, Bahasa Melayu, Bahasa Indonesia, Hokkien Dialect, Hakka

Graduated MBBS from the National University Of Singapore in 1973. Trained in gastroenterology in UK (Oxford). Member of the Royal Colleges of Physicians of the United Kingdom.(1979) Fellow of the Royal Physicians of Edinburgh (1990) and London.(1992) Fellow of the Academy Of Medicine Singapore (Gastroenterology) (1983). Was a faculty member of the Department of Medicine, National University Of Singapore from 1983- 1995. He was made Associated Professor 1990. Has been practicing Gastroenterology and Hepatology at the Mt Elizabeth Medical Centre since 1995.

He has collaborated on many international studies on pegylated interferon, lamivudine, and combination therapies and his current research interests include chronic hepatitis B and C infections, liver cancer, irritable bowel syndrome, and ulcerative colitis and related disorders.

Dr Guan is consultant and advisory board member in the field of viral hepatitis research studies for international pharmaceutical companies involved in the manufacture of drugs used for hepatitis B treatment.



  • National Advisory and Scientific committee on Hepatitis and related disorders (Ministry of Health)
  • Medicines Advisory Committee (Health Science Authority)
  • Parkway International Ethics Committee (Parkway Health Care).

Past Member Singapore Medical Council,

  • Gastroenterology Specialist Training Committee,(Ministry of Health)
  • National Advisory Committee on Transplantation (Ministry of Health)
  • Hepatobiliary Subcommittee of the National Committee on Cancer Care.

Other Organisations: Active member of  regional and international professional organizations like the Asia Pacific Association of the Study of Liver Diseases (APASL), International Association of the Study of the Liver (IASL), British Society of Gastroenterology (BSG). He has served in several APASL working committees on management guidelines for chronic hepatits B and chronic hepatitis C infections in the region and is a member of the Asia Pacific Hepatitis B management Advisory Board.

He is widely recognized as an expert in the field of viral hepatitis in the Asia Pacific region and has regularly been invited to give talks on viral hepatitis and liver diseases at both local and regional conferences. Besides being a part-time lecturer to several organisations in Singapore, Dr Guan has been a member of teaching faculties in local and regional scientific meetings. He organizes and/or assists in numerous national and regional scientific meetings for physicians as well as educational meetings for the public.  He lectures extensively at seminars, study groups, and to general practitioners locally as well as regionally.

Dr Guan has published more than 100 scientific articles, more than 150 abstracts and several chapters of books.  He is an editorial board member of Hepatology International, Hepatitis World, Digestive Tract, and the Bangladesh Journal of Gastroenterology and the editor-in-chief of Management of Common Gastroenterological Problems: A Malaysia & Singapore Perspective, a book on local gastroenterological problems. He serves on several editorial committees of journals, newsletters and drug directories both locally and regionally. He is currently a reviewer for the Journal of Gastroenterology and Hepatology, Journal of Viral Hepatitis, Alimentary Pharmacology and Therapeutics, and Hepatology International, International Journal of Hepatology among others.